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dc.contributor.authorBurgess, Stephen
dc.contributor.authorChirinos, Julio A
dc.contributor.authorDamrauer, Scott M
dc.contributor.authorGill, Dipender
dc.date.accessioned2022-02-09T00:30:18Z
dc.date.available2022-02-09T00:30:18Z
dc.date.issued2022-05-06
dc.identifier.issn2574-8300
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/333752
dc.description.abstractPulse pressure (PP), the difference between systolic blood pressure (SBP) and diastolic blood pressure (DBP), arises due to pulsatile ejection of blood from the left ventricle. Previous observational studies have identified an inverse association of PP with aortic diameter1, and positive associations of PP with aortic wall stiffness and thickness2. However, it is not known whether these associations reflect a causal effect of PP on the risk of AAA, an effect of the aorta on PP, a shared etiology, or confounding from environmental factors.
dc.publisherOvid Technologies (Wolters Kluwer Health)
dc.rightsAll Rights Reserved
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserved
dc.titleGenetically Predicted Pulse Pressure and Risk of Abdominal Aortic Aneurysm: a Mendelian Randomization Analysis.
dc.typeArticle
dc.publisher.departmentMrc Biostatistics Unit
dc.date.updated2022-02-07T15:05:48Z
prism.publicationNameCirc Genom Precis Med
dc.identifier.doi10.17863/CAM.81169
dcterms.dateAccepted2022-02-03
rioxxterms.versionofrecord10.1161/CIRCGEN.121.003575
rioxxterms.versionAM
dc.contributor.orcidBurgess, Stephen [0000-0001-5365-8760]
dc.contributor.orcidChirinos, Julio A [0000-0001-9035-5670]
dc.contributor.orcidDamrauer, Scott M [0000-0001-8009-1632]
dc.contributor.orcidGill, Dipender [0000-0001-7312-7078]
dc.identifier.eissn2574-8300
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (204623/Z/16/Z)
cam.issuedOnline2022-05-06
cam.orpheus.successWed May 25 11:13:15 BST 2022 - Embargo updated
cam.orpheus.counter5
cam.depositDate2022-02-07
pubs.licence-identifierapollo-deposit-licence-2-1
pubs.licence-display-nameApollo Repository Deposit Licence Agreement
rioxxterms.freetoread.startdate2022-11-06


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