Show simple item record

dc.contributor.authorvan Vollenhoven, Ronald F
dc.contributor.authorBertsias, George
dc.contributor.authorDoria, Andrea
dc.contributor.authorIsenberg, David
dc.contributor.authorMorand, Eric
dc.contributor.authorPetri, Michelle A
dc.contributor.authorPons-Estel, Bernardo A
dc.contributor.authorRahman, Anisur
dc.contributor.authorUgarte-Gil, Manuel Francisco
dc.contributor.authorVoskuyl, Alexandre
dc.contributor.authorArnaud, Laurent
dc.contributor.authorBruce, Ian N
dc.contributor.authorCervera, Ricard
dc.contributor.authorCostedoat-Chalumeau, Nathalie
dc.contributor.authorGordon, Caroline
dc.contributor.authorHoussiau, Frédéric A
dc.contributor.authorMosca, Marta
dc.contributor.authorSchneider, Matthias
dc.contributor.authorWard, Michael M
dc.contributor.authorAlarcon, Graciela
dc.contributor.authorAringer, Martin
dc.contributor.authorAskenase, Anka
dc.contributor.authorBae, Sang-Cheol
dc.contributor.authorBootsma, Hendrika
dc.contributor.authorBoumpas, Dimitrios T
dc.contributor.authorBrunner, Hermine
dc.contributor.authorClarke, Ann Elaine
dc.contributor.authorConey, Cindy
dc.contributor.authorCzirják, László
dc.contributor.authorDörner, Thomas
dc.contributor.authorFaria, Raquel
dc.contributor.authorFischer, Rebecca
dc.contributor.authorFritsch-Stork, Ruth
dc.contributor.authorInanc, Murat
dc.contributor.authorJacobsen, Søren
dc.contributor.authorJayne, David
dc.contributor.authorKuhn, Annegret
dc.contributor.authorvan Leeuw, Bernadette
dc.contributor.authorLimper, Maarten
dc.contributor.authorMariette, Xavier
dc.contributor.authorNavarra, Sandra
dc.contributor.authorNikpour, Mandana
dc.contributor.authorOlesinska, Marzena Helena
dc.contributor.authorPons-Estel, Guillermo
dc.contributor.authorRomero-Diaz, Juanita
dc.contributor.authorRubio, Blanca
dc.contributor.authorSchoenfeld, Yehuda
dc.contributor.authorBonfá, Eloisa
dc.contributor.authorSmolen, Josef
dc.contributor.authorTeng, YK Onno
dc.contributor.authorTincani, Angela
dc.contributor.authorTsang-A-Sjoe, Michel
dc.contributor.authorVasconcelos, Carlos
dc.contributor.authorVoss, Anne
dc.contributor.authorWerth, Victoria P
dc.contributor.authorZakharhova, Elena
dc.contributor.authorAranow, Cynthia
dc.date.accessioned2022-02-14T14:00:34Z
dc.date.available2022-02-14T14:00:34Z
dc.date.issued2021-11
dc.date.submitted2021-07-12
dc.identifier.issn2053-8790
dc.identifier.otherlupus-2021-000538
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/334001
dc.description.abstractOBJECTIVE: To achieve consensus on a definition of remission in SLE (DORIS). BACKGROUND: Remission is the stated goal for both patient and caregiver, but consensus on a definition of remission has been lacking. Previously, an international task force consisting of patient representatives and medical specialists published a framework for such a definition, without reaching a final recommendation. METHODS: Several systematic literature reviews were performed and specific research questions examined in suitably chosen data sets. The findings were discussed, reformulated as recommendations and voted on. RESULTS: Based on data from the literature and several SLE-specific data sets, a set of recommendations was endorsed. Ultimately, the DORIS Task Force recommended a single definition of remission in SLE, based on clinical systemic lupus erythematosus disease activitiy index (SLEDAI)=0, Evaluator's Global Assessment <0.5 (0-3), prednisolone 5 mg/day or less, and stable antimalarials, immunosuppressives, and biologics. CONCLUSION: The 2021 DORIS definition of remission in SLE is recommended for use in clinical care, education, and research including clinical trials and observational studies.
dc.languageen
dc.publisherBMJ
dc.subjectEpidemiology and outcomes
dc.subject1506
dc.subject2257
dc.subjectlupus erythematosus
dc.subjectsystemic
dc.subjectoutcome assessment
dc.subjecthealthcare
dc.subjecttherapeutics
dc.title2021 DORIS definition of remission in SLE: final recommendations from an international task force.
dc.typeArticle
dc.date.updated2022-02-14T14:00:33Z
prism.issueIdentifier1
prism.publicationNameLupus Sci Med
prism.volume8
dc.identifier.doi10.17863/CAM.81413
dcterms.dateAccepted2021-11-04
rioxxterms.versionofrecord10.1136/lupus-2021-000538
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc/4.0/
rioxxterms.licenseref.startdate2021-11-23
dc.contributor.orcidvan Vollenhoven, Ronald F [0000-0001-6438-8663]
dc.contributor.orcidDoria, Andrea [0000-0003-0548-4983]
dc.contributor.orcidMorand, Eric [0000-0002-9507-3338]
dc.contributor.orcidPetri, Michelle A [0000-0003-1441-5373]
dc.contributor.orcidPons-Estel, Bernardo A [0000-0003-2518-0266]
dc.contributor.orcidUgarte-Gil, Manuel Francisco [0000-0003-1728-1999]
dc.contributor.orcidArnaud, Laurent [0000-0002-8077-8394]
dc.contributor.orcidBruce, Ian N [0000-0003-3047-500X]
dc.contributor.orcidHoussiau, Frédéric A [0000-0003-1451-083X]
dc.contributor.orcidAringer, Martin [0000-0003-4471-8375]
dc.contributor.orcidBae, Sang-Cheol [0000-0003-4658-1093]
dc.contributor.orcidBoumpas, Dimitrios T [0000-0002-9812-4671]
dc.contributor.orcidBrunner, Hermine [0000-0001-9478-2987]
dc.contributor.orcidDörner, Thomas [0000-0002-6478-7725]
dc.contributor.orcidJacobsen, Søren [0000-0002-5654-4993]
dc.contributor.orcidJayne, David [0000-0002-1712-0637]
dc.contributor.orcidTeng, YK Onno [0000-0001-9920-2195]
dc.contributor.orcidTsang-A-Sjoe, Michel [0000-0002-4982-3505]
dc.contributor.orcidWerth, Victoria P [0000-0003-3030-5369]
dc.contributor.orcidAranow, Cynthia [0000-0001-9299-0053]
dc.identifier.eissn2053-8790
pubs.funder-project-idUCB Pharma (n/a)
pubs.funder-project-idGlaxoSmithKline (n/a)
cam.issuedOnline2021-11-24
rioxxterms.freetoread.startdate2021-11-23
rioxxterms.freetoread.startdate2021-11-23


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record