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dc.contributor.authorSherkow, Jacob S
dc.contributor.authorBarker, Katharine B
dc.contributor.authorBraverman, Irus
dc.contributor.authorCook-Deegan, Robert
dc.contributor.authorDurbin, Richard
dc.contributor.authorEaster, Carla L
dc.contributor.authorGoldstein, Melissa M
dc.contributor.authorHudson, Maui
dc.contributor.authorKress, W John
dc.contributor.authorLewin, Harris A
dc.contributor.authorMathews, Debra JH
dc.contributor.authorMcCarthy, Catherine
dc.contributor.authorMcCartney, Ann M
dc.contributor.authorda Silva, Manuela
dc.contributor.authorTorrance, Andrew W
dc.contributor.authorGreely, Henry T
dc.date.accessioned2022-02-20T02:02:48Z
dc.date.available2022-02-20T02:02:48Z
dc.date.issued2022-01-25
dc.identifier.issn0027-8424
dc.identifier.otherPMC8795529
dc.identifier.other35042809
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/334244
dc.description.abstractThe Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole-genome sequences of representatives from all eukaryotic species on Earth. In addition to the project's technical and organizational challenges, it also faces complicated ethical, legal, and social issues. This paper, from members of the EBP's Ethical, Legal, and Social Issues (ELSI) Committee, catalogs these ELSI concerns arising from EBP. These include legal issues, such as sample collection and permitting; the applicability of international treaties, such as the Convention on Biological Diversity and the Nagoya Protocol; intellectual property; sample accessioning; and biosecurity and ethical issues, such as sampling from the territories of Indigenous peoples and local communities, the protection of endangered species, and cross-border collections, among several others. We also comment on the intersection of digital sequence information and data rights. More broadly, this list of ethical, legal, and social issues for large-scale genomic sequencing projects may be useful in the consideration of ethical frameworks for future projects. While we do not-and cannot-provide simple, overarching solutions for all the issues raised here, we conclude our perspective by beginning to chart a path forward for EBP's work.
dc.languageeng
dc.publisherProceedings of the National Academy of Sciences
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourcenlmid: 7505876
dc.sourceessn: 1091-6490
dc.subjectBiodiversity
dc.subjectGenomics
dc.subjectEthics
dc.subjectEbp
dc.subjectElsi
dc.subjectAnimals
dc.subjectHumans
dc.subjectEthics, Research
dc.subjectEndangered Species
dc.subjectBiosecurity
dc.titleEthical, legal, and social issues in the Earth BioGenome Project.
dc.typeArticle
dc.date.updated2022-02-20T02:02:47Z
prism.issueIdentifier4
prism.publicationNameProc Natl Acad Sci U S A
prism.volume119
dc.identifier.doi10.17863/CAM.81657
rioxxterms.versionofrecord10.1073/pnas.2115859119
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidSherkow, Jacob S [0000-0002-9724-9261]
dc.contributor.orcidBraverman, Irus [0000-0002-4352-001X]
dc.contributor.orcidCook-Deegan, Robert [0000-0002-8251-4237]
dc.contributor.orcidDurbin, Richard [0000-0002-9130-1006]
dc.contributor.orcidGoldstein, Melissa M [0000-0001-5576-9018]
dc.contributor.orcidKress, W John [0000-0002-0140-5267]
dc.contributor.orcidLewin, Harris A [0000-0002-1043-7287]
dc.contributor.orcidMathews, Debra JH [0000-0002-4897-7617]
dc.contributor.orcidda Silva, Manuela [0000-0001-6073-8929]
dc.contributor.orcidGreely, Henry T [0000-0002-1105-6734]
dc.identifier.eissn1091-6490
cam.issuedOnline2022-01-18


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International