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Frail by different measures: a comparison of 8-year mortality in The Irish Longitudinal Study on Ageing (TILDA).

Published version
Peer-reviewed

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Authors

Romero-Ortuno, Roman  ORCID logo  https://orcid.org/0000-0002-3882-7447
Hartley, Peter 
Kenny, Rose Anne 
O'Halloran, Aisling M 

Abstract

PURPOSE: We compared the ability of four frailty identification tools (frailty phenotype: FP; FRAIL scale; 32-item Frailty Index: FI; and Clinical Frailty Scale: CFS) to predict 8-year mortality in TILDA. METHODS: We included wave 1 (2010) participants with data for all four tools. Mortality was ascertained at wave 5 (2018). Age, sex and education-adjusted binary logistic regression models were computed. RESULTS: At baseline, there were 5700 participants (mean age 63, range 50-98, 54% women). Frailty prevalences were 2.3% by FRAIL, 3.8% by FP, 10.9% by CFS, and 12.8% by FI. Mortality was 41.2%, 44.9%, 25.3% and 27.0%, respectively. The highest adjusted OR for mortality was for FRAIL (OR 4.48, 95% CI 2.93-6.85, P < 0.001), followed by FP (OR 3.55, 95% CI 2.52-5.00, P < 0.001), FI (OR 2.10, 95% CI 1.68-2.62, P < 0.001), and CFS (OR 1.88, 95% CI 1.48-2.38, P < 0.001). CONCLUSIONS: All tools significantly predicted mortality, but FRAIL and FP seemed more specific.

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Keywords

Comparative study, Frailty, Longitudinal study, Mortality, Older people, Aged, Aging, Female, Frail Elderly, Frailty, Geriatric Assessment, Humans, Longitudinal Studies, Male

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Publisher

Springer Science and Business Media LLC
Sponsorship
Science Foundation Ireland (18/FRL/6188)