Semiconducting Polymers for Neural Applications.
American Chemical Society (ACS)
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Dimov, I. B., Moser, M., Malliaras, G. G., & McCulloch, I. (2022). Semiconducting Polymers for Neural Applications.. Chem Rev, (acs.chemrev.1c00685) https://doi.org/10.1021/acs.chemrev.1c00685
Electronically interfacing with the nervous system for the purposes of health diagnostics and therapy, sports performance monitoring, or device control has been a subject of intense academic and industrial research for decades. This trend has only increased in recent years, with numerous high-profile research initiatives and commercial endeavors. An important research theme has emerged as a result, which is the incorporation of semiconducting polymers in various devices that communicate with the nervous system─from wearable brain-monitoring caps to penetrating implantable microelectrodes. This has been driven by the potential of this broad class of materials to improve the electrical and mechanical properties of the tissue-device interface, along with possibilities for increased biocompatibility. In this review we first begin with a tutorial on neural interfacing, by reviewing the basics of nervous system function, device physics, and neuroelectrophysiological techniques and their demands, and finally we give a brief perspective on how material improvements can address current deficiencies in this system. The second part is a detailed review of past work on semiconducting polymers, covering electrical properties, structure, synthesis, and processing.
European Research Council (610115)
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External DOI: https://doi.org/10.1021/acs.chemrev.1c00685
This record's URL: https://www.repository.cam.ac.uk/handle/1810/334459
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