Travel-related infections presenting in Europe: A 20-year analysis of EuroTravNet surveillance data.
Authors
Grobusch, Martin P
Weld, Leisa
Goorhuis, Abraham
Hamer, Davidson H
Schunk, Mirjam
Jordan, Sabine
Mockenhaupt, Frank P
Chappuis, François
Asgeirsson, Hilmir
Caumes, Eric
Jensenius, Mogens
van Genderen, Perry JJ
Castelli, Francesco
López-Velez, Rogelio
Field, Vanessa
Bottieau, Emmanuel
Molina, Israel
Rapp, Christophe
Ménendez, Marta Díaz
Larsen, Carsten S
Malvy, Denis
Lalloo, David
Gobbi, Federico
Florescu, Simin A
Gautret, Philippe
Schlagenhauf, Patricia
for EuroTravNet
Publication Date
2021-02Journal Title
Lancet Reg Health Eur
ISSN
2666-7762
Publisher
Elsevier BV
Volume
1
Language
eng
Type
Article
This Version
VoR
Metadata
Show full item recordCitation
Grobusch, M. P., Weld, L., Goorhuis, A., Hamer, D. H., Schunk, M., Jordan, S., Mockenhaupt, F. P., et al. (2021). Travel-related infections presenting in Europe: A 20-year analysis of EuroTravNet surveillance data.. Lancet Reg Health Eur, 1 https://doi.org/10.1016/j.lanepe.2020.100001
Description
Funder: Centers for Disease Control and Prevention
Abstract
BACKGROUND: Disease epidemiology of (re-)emerging infectious diseases is changing rapidly, rendering surveillance of travel-associated illness important. METHODS: We evaluated travel-related illness encountered at EuroTravNet clinics, the European surveillance sub-network of GeoSentinel, between March 1, 1998 and March 31, 2018. FINDINGS: 103,739 ill travellers were evaluated, including 11,239 (10.8%) migrants, 89,620 (86.4%) patients seen post-travel, and 2,880 (2.8%) during and after travel. Despite increasing numbers of patient encounters over 20 years, the regions of exposure by year of clinic visits have remained stable. In 5-year increments, greater proportions of patients were migrants or visiting friends and relatives (VFR); business travel-associated illness remained stable; tourism-related illness decreased. Falciparum malaria was amongst the most-frequently diagnosed illnesses with 5,254 cases (5.1% of all patients) and the most-frequent cause of death (risk ratio versus all other illnesses 2.5:1). Animal exposures requiring rabies post-exposure prophylaxis increased from 0.7% (1998-2002) to 3.6% (2013-2018). The proportion of patients with seasonal influenza increased from zero in 1998-2002 to 0.9% in 2013-2018. There were 44 cases of viral haemorrhagic fever, most during the past five years. Arboviral infection numbers increased significantly as did the range of presenting arboviral diseases, dengue and chikungunya diagnoses increased by 2.6% and 1%, respectively. INTERPRETATION: Travel medicine must adapt to serve the changing profile of travellers, with an increase in migrants and persons visiting relatives and friends and the strong emergence of vector-borne diseases, with potential for further local transmission in Europe. FUNDING: This project was supported by a cooperative agreement (U50CK00189) between the Centers for Disease Control and Prevention to the International Society of Travel Medicine (ISTM) and funding from the ISTM and the Public Health Agency of Canada.
Keywords
Infectious diseases, Travel, Sentinel Surveillance, Geosentinel, Eurotravnet
Sponsorship
Medical Research Council (G0701652)
Identifiers
PMC8454853, 35081179
External DOI: https://doi.org/10.1016/j.lanepe.2020.100001
This record's URL: https://www.repository.cam.ac.uk/handle/1810/334481
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