Stem cells "aclymatise" to regenerate the blood system.

Lisi-Vega, Livia E; Méndez-Ferrer, Simón

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Authors

Lisi-Vega, Livia E

Méndez-Ferrer, Simón

Publication Date

2022-04-19

Journal Title

EMBO J

ISSN

0261-4189

Publisher

EMBO

Type

Article

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Citation

Lisi-Vega, L. E., & Méndez-Ferrer, S. (2022). Stem cells "aclymatise" to regenerate the blood system.. EMBO J https://doi.org/10.15252/embj.2022110942

Abstract

How blood stem cells balance fate decisions between quiescence maintenance and differentiation during recovery from cancer treatment remains poorly understood. A recent study by Umemoto et al (2022) uncovers an unexpected linkage between metabolic and epigenetic regulation of haematopoiesis, suggesting new targets in haematopoietic regeneration, with possible implications in leukaemogenesis and therapy resistance.

Identifiers

External DOI: https://doi.org/10.15252/embj.2022110942

This record's URL: https://www.repository.cam.ac.uk/handle/1810/334791

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Licence URL: http://www.rioxx.net/licenses/all-rights-reserved

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