Multimodal Treatment of a Canine Lingual Melanoma Using a Combination of Immunotherapy and a Tyrosine Kinase Inhibitors.
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Publication Date
2022-01-29Journal Title
Veterinary sciences
ISSN
2306-7381
Volume
9
Issue
2
Language
eng
Type
Other
This Version
VoR
Metadata
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Berry, A., Hayes, A., Schiavo, L., & Dobson, J. (2022). Multimodal Treatment of a Canine Lingual Melanoma Using a Combination of Immunotherapy and a Tyrosine Kinase Inhibitors.. [Other]. https://doi.org/10.3390/vetsci9020054
Abstract
A 9-year-old female neutered Miniature Schnauzer was diagnosed with a lingual malignant melanoma on the basis of incisional biopsy and histopathology. The patient was initially given a guarded prognosis of a few months' survival as surgical treatment options were declined by the owner. In order to control the disease a combination treatment of immunotherapy and tyrosine kinase inhibitors was initiated. The mass showed a marked and sustained reduction in size, whilst preserving quality of life for the patient, with a survival at the time of writing of 15 months since diagnosis. This experience suggests that combination therapy for oral malignant melanoma using immunotherapy and tyrosine kinase inhibitors may be successful in some patients and warrants further investigation.
Keywords
Immunotherapy, Tyrosine kinase inhibitor, Tki, Lingual Malignant Melanoma
Identifiers
35202307, PMC8879531
External DOI: https://doi.org/10.3390/vetsci9020054
This record's DOI: https://doi.org/10.17863/CAM.82853
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