Early detection of cancer.
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Authors
Publication Date
2022-03-18Journal Title
Science
ISSN
0036-8075
Publisher
American Association for the Advancement of Science (AAAS)
Type
Article
This Version
AM
Metadata
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Crosby, D., Bhatia, S., Brindle, K., Coussens, L. M., Dive, C., Emberton, M., Esener, S., et al. (2022). Early detection of cancer.. Science https://doi.org/10.1126/science.aay9040
Abstract
Survival improves when cancer is detected early. However, ~50% of cancers are at an advanced stage when diagnosed. Early detection of cancer or precancerous change allows early intervention to try to slow or prevent cancer development and lethality. To achieve early detection of all cancers, numerous challenges must be overcome. It is vital to better understand who is at greatest risk of developing cancer. We also need to elucidate the biology and trajectory of precancer and early cancer to identify consequential disease that requires intervention. Insights must be translated into sensitive and specific early detection technologies and be appropriately evaluated to support practical clinical implementation. Interdisciplinary collaboration is key; advances in technology and biological understanding highlight that it is time to accelerate early detection research and transform cancer survival.
Sponsorship
Cancer Research UK (CB4330)
Identifiers
External DOI: https://doi.org/10.1126/science.aay9040
This record's URL: https://www.repository.cam.ac.uk/handle/1810/335445
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Publisher's own licence
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