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dc.contributor.authorTang, Mingwei
dc.contributor.authorHan, Yubing
dc.contributor.authorYe, Dehao
dc.contributor.authorZhang, Qianwei
dc.contributor.authorPang, Chenlei
dc.contributor.authorLiu, Xiaowei
dc.contributor.authorShen, Weidong
dc.contributor.authorMa, Yaoguang
dc.contributor.authorKaminski, Clemens
dc.contributor.authorLiu, Xu
dc.contributor.authorYang, Qing
dc.date.accessioned2022-03-31T18:01:01Z
dc.date.available2022-03-31T18:01:01Z
dc.date.issued2022-03
dc.date.submitted2021-09-02
dc.identifier.issn2198-3844
dc.identifier.otheradvs3469
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/335606
dc.descriptionFunder: Zhejiang University Education Foundation Global Partnership Fund
dc.descriptionFunder: Open Foundation of the State Key Laboratory of Modern Optical Instrumentation
dc.descriptionFunder: Zhejiang University Micro‐Nano Fabrication Center
dc.description.abstractContinued research in fields such as materials science and biomedicine requires the development of a super-resolution imaging technique with a large field of view (FOV) and deep subwavelength resolution that is compatible with both fluorescent and nonfluorescent samples. Existing on-chip super-resolution methods exclusively focus on either fluorescent or nonfluorescent imaging, and, as such, there is an urgent requirement for a more general technique that is capable of both modes of imaging. In this study, to realize labeled and label-free super-resolution imaging on a single scalable photonic chip, a universal super-resolution imaging method based on the tunable virtual-wavevector spatial frequency shift (TVSFS) principle is introduced. Using this principle, imaging resolution can be improved more than threefold over the diffraction limit of a linear optical system. Here, diffractive units are fabricated on the chip's surface to provide wavevector-variable evanescent wave illumination, enabling tunable spatial frequency shifts in the Fourier space. A large FOV and resolutions of λ/4.7 and λ/7.1 were achieved for label-free and fluorescently labeled samples using a gallium phosphide (GaP) chip. With its large FOV, compatibility with different imaging modes, and monolithic integration, the proposed TVSFS chip may advance fields such as cell engineering, precision industry inspection, and chemical research.
dc.languageen
dc.publisherWiley
dc.subjectResearch Article
dc.subjectResearch Articles
dc.subjectfield of view
dc.subjectlabel‐free
dc.subjectsuper‐resolution chips
dc.subjecttunable virtual‐wavevector spatial frequency shift
dc.titleHigh-Refractive-Index Chip with Periodically Fine-Tuning Gratings for Tunable Virtual-Wavevector Spatial Frequency Shift Universal Super-Resolution Imaging.
dc.typeArticle
dc.date.updated2022-03-31T18:01:01Z
prism.issueIdentifier9
prism.publicationNameAdv Sci (Weinh)
prism.volume9
dc.identifier.doi10.17863/CAM.83037
rioxxterms.versionofrecord10.1002/advs.202103835
rioxxterms.versionAO
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidTang, Mingwei [0000-0002-2091-2205]
dc.contributor.orcidKaminski, Clemens [0000-0002-5194-0962]
dc.contributor.orcidYang, Qing [0000-0001-5324-4832]
dc.identifier.eissn2198-3844
pubs.funder-project-idNational Natural Science Foundation of China (61822510, 61735017, 62020106002, 31901059, 62005250)
pubs.funder-project-idNational Key Research and Development Program of China (2018YFE0119000)
cam.issuedOnline2022-01-27


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