A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia.
View / Open Files
Publication Date
2022-03-18Journal Title
NPJ Schizophr
ISSN
2334-265X
Publisher
Springer Science and Business Media LLC
Volume
8
Issue
1
Language
eng
Type
Article
This Version
VoR
Metadata
Show full item recordCitation
Osimo, E. F., Brugger, S. P., Thomas, E. L., & Howes, O. D. (2022). A cross-sectional MR study of body fat volumes and distribution in chronic schizophrenia.. NPJ Schizophr, 8 (1) https://doi.org/10.1038/s41537-022-00233-z
Description
Funder: RCUK | Medical Research Council
Funder: National Institute for Health Research (NIHR)
Abstract
People with schizophrenia show higher risk for abdominal obesity than the general population, which could contribute to excess mortality. However, it is unclear whether this is driven by alterations in abdominal fat partitioning. Here, we test the hypothesis that individuals with schizophrenia show a higher proportion of visceral to total body fat measured using magnetic resonance imaging (MRI). We recruited 38 participants with schizophrenia and 38 healthy controls matched on age, sex, ethnicity, and body mass index. We found no significant differences in body fat distribution between groups, suggesting that increased abdominal obesity in schizophrenia is not associated with altered fat distribution.
Identifiers
35304889, PMC8933542
External DOI: https://doi.org/10.1038/s41537-022-00233-z
This record's URL: https://www.repository.cam.ac.uk/handle/1810/336250
Statistics
Total file downloads (since January 2020). For more information on metrics see the
IRUS guide.