Magnetic resonance spectroscopy ex vivo: A short historical review.
Authors
Publication Date
2022-04-12Journal Title
NMR Biomed
ISSN
0952-3480
Publisher
Wiley
Language
en
Type
Article
This Version
AO
VoR
Metadata
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Griffiths, J. R. (2022). Magnetic resonance spectroscopy ex vivo: A short historical review.. NMR Biomed https://doi.org/10.1002/nbm.4740
Abstract
Over the last half century, there have been several periods during which magnetic resonance spectroscopy (MRS) has been used ex vivo, for a variety of reasons, on samples such as microorganisms, cells, animal or human tissue, tissue extracts or biological fluids. These studies began in the days before the acronym MRS had been invented, when all such methods were still called nuclear magnetic resonance (NMR), and have extended to the present day. I will describe the historical development of NMR methods used ex vivo, their influences on the development of MRS in vivo, and their longer-term uses. All the interpretations will be personal, based on what I saw, or discussed with colleagues at the time.
Keywords
REVIEW ARTICLE, REVIEW ARTICLES, chemometrics, metabolomics, metabonomics, MRS ex vivo
Identifiers
nbm4740
External DOI: https://doi.org/10.1002/nbm.4740
This record's URL: https://www.repository.cam.ac.uk/handle/1810/336414
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Licence:
http://creativecommons.org/licenses/by-nc-nd/4.0/
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