HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy

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dc.contributor.authorKemp, Steven A
dc.contributor.authorCharles, Oscar J
dc.contributor.authorDerache, Anne
dc.contributor.authorSmidt, Werner
dc.contributor.authorMartin, Darren P
dc.contributor.authorIwuji, Collins
dc.contributor.authorAdamson, John
dc.contributor.authorGovender, Katya
dc.contributor.authorde Oliveira, Tulio
dc.contributor.authorDabis, Francois
dc.contributor.authorPillay, Deenan
dc.contributor.authorGoldstein, Richard A
dc.contributor.authorGupta, Ravindra K
dc.date.accessioned2022-04-26T23:30:12Z
dc.date.available2022-04-26T23:30:12Z
dc.date.issued2022-06-28
dc.identifier.issn2150-7511
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/336482
dc.description.abstract<jats:p>HIV-1 infections are most commonly initiated with a single founder virus and are characterized by extensive inter- and intraparticipant genetic diversity. However, existing literature on HIV-1 intrahost population dynamics is largely limited to untreated infections, predominantly in subtype B-infected individuals.</jats:p>
dc.publisherAmerican Society for Microbiology
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectantiretroviral resistance
dc.subjectclinical failure
dc.subjectdrug resistance evolution
dc.subjecthuman immunodeficiency virus
dc.subjectAnti-HIV Agents
dc.subjectAnti-Retroviral Agents
dc.subjectDrug Resistance, Viral
dc.subjectHIV Infections
dc.subjectHIV Seropositivity
dc.subjectHIV-1
dc.subjectHumans
dc.subjectViral Load
dc.subjectViremia
dc.titleHIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy
dc.typeArticle
dc.publisher.departmentDepartment of Medicine
dc.date.updated2022-04-25T10:26:19Z
prism.publicationNamemBio
dc.identifier.doi10.17863/CAM.83900
dcterms.dateAccepted2022-04-21
rioxxterms.versionofrecord10.1128/mbio.00269-22
rioxxterms.versionVoR
dc.contributor.orcidKemp, Steven [0000-0001-7077-6793]
dc.contributor.orcidGupta, Ravindra [0000-0001-9751-1808]
dc.identifier.eissn2150-7511
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (108082/A/15/Z)
cam.issuedOnline2022-04-21
cam.depositDate2022-04-25
pubs.licence-identifierapollo-deposit-licence-2-1
pubs.licence-display-nameApollo Repository Deposit Licence Agreement


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International