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HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy

Published version
Peer-reviewed

Type

Article

Change log

Authors

Kemp, Steven A 
Charles, Oscar J 
Derache, Anne 
Smidt, Werner 
Martin, Darren P 

Abstract

jats:pHIV-1 infections are most commonly initiated with a single founder virus and are characterized by extensive inter- and intraparticipant genetic diversity. However, existing literature on HIV-1 intrahost population dynamics is largely limited to untreated infections, predominantly in subtype B-infected individuals.</jats:p>

Description

Keywords

antiretroviral resistance, clinical failure, drug resistance evolution, human immunodeficiency virus, Anti-HIV Agents, Anti-Retroviral Agents, Drug Resistance, Viral, HIV Infections, HIV Seropositivity, HIV-1, Humans, Viral Load, Viremia

Journal Title

mBio

Conference Name

Journal ISSN

2150-7511
2150-7511

Volume Title

Publisher

American Society for Microbiology
Sponsorship
Wellcome Trust (108082/A/15/Z)