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dc.contributor.authorStrakova, Andrea
dc.contributor.authorBaez-Ortega, Adrian
dc.contributor.authorWang, Jinhong
dc.contributor.authorMurchison, Elizabeth P
dc.date.accessioned2022-05-19T23:30:26Z
dc.date.available2022-05-19T23:30:26Z
dc.date.issued2022-07-03
dc.identifier.issn0042-4900
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337323
dc.description.abstractBACKGROUND: The canine transmissible venereal tumour (CTVT) is a contagious cancer spread by the direct transfer of living cancer cells. CTVT usually spreads during mating, manifesting as genital tumours. However, oronasal CTVT is also occasionally observed, and presumably arises through oronasal contact with genital CTVT tumours during sniffing and licking. METHODS: Given that sniffing and licking transmission behaviours may differ between sexes, we investigated whether oronasal CTVT shows sex disparity. RESULTS: Twenty-seven of 32 (84%) primary oronasal tumours in a CTVT tumour database occurred in males. In addition, 53 of 65 (82%) primary oronasal CTVT tumours reported in the published literature involved male hosts. These findings suggest that male dogs are at four to five times greater risk of developing primary oronasal CTVT than females. This disparity may be due to sex differences in licking and sniffing activity, perhaps also influenced by sex differences in CTVT accessibility for these behaviours. CONCLUSION: Although oronasal CTVT is rare, it should be considered as a possible diagnosis for oronasal tumours, particularly in male dogs.
dc.description.sponsorshipInternational Canine Health Postgraduate Student Inspiration Award from the Kennel Club Charitable Trust
dc.publisherWiley
dc.rightsAll Rights Reserved
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserved
dc.titleSex disparity in oronasal presentations of canine transmissible venereal tumour.
dc.typeArticle
dc.publisher.departmentDepartment of Veterinary Medicine
dc.date.updated2022-05-18T22:29:31Z
prism.publicationNameVet Rec
dc.identifier.doi10.17863/CAM.84737
dcterms.dateAccepted2022-04-19
rioxxterms.versionofrecord10.1002/vetr.1794
rioxxterms.versionAM
dc.contributor.orcidStrakova, Andrea [0000-0001-6221-5515]
dc.identifier.eissn2042-7670
rioxxterms.typeJournal Article/Review
pubs.funder-project-idWellcome Trust (102942/Z/13/Z)
cam.issuedOnline2022-07-03
cam.orpheus.successMon Jul 11 08:50:17 BST 2022 - Embargo updated
cam.orpheus.counter6
cam.depositDate2022-05-18
pubs.licence-identifierapollo-deposit-licence-2-1
pubs.licence-display-nameApollo Repository Deposit Licence Agreement
rioxxterms.freetoread.startdate2023-07-03


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