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dc.contributor.authorCorbett, Gareth
dc.contributor.authorPugh, Peter
dc.contributor.authorHerre, Jurgen
dc.contributor.authorSee, Teik Choon
dc.contributor.authorde Monteverde-Robb, David
dc.contributor.authorTorrejon Torres, Rafael
dc.contributor.authorSaunders, Rhodri
dc.contributor.authorLeonard, Catherine
dc.contributor.authorPrakash, Amit
dc.date.accessioned2022-05-20T10:00:06Z
dc.date.available2022-05-20T10:00:06Z
dc.date.issued2022
dc.date.submitted2022-02-01
dc.identifier.issn2296-858X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337338
dc.description.abstractBackground: Capnography has been associated with a reduced incidence of events related to respiratory compromise during procedural sedation. Methods: A prospective service evaluation was conducted at a large United Kingdom (UK) teaching hospital to assess the impact of capnography on patient safety within four speciality services: bronchoscopy, endoscopy, interventional cardiology, and interventional radiology. Events were defined as provided by the World Society of Intravenous Anaesthesia. One thousand four hundred one patients were enrolled in the evaluation, with 666 patients before and 735 after implementation of capnography. Data was entered as a convenience sample on site in an offline data-collection tool. Results were assessed for the relative reduction in the incidence and resulting adjusted odds ratio for the combined incidence of oxygen desaturation (75-90% for <60s), severe oxygen desaturation (<75% at any time) or prolonged oxygen desaturation (<90% for >60s), bradycardia (>25% from baseline) and tachycardia (>25% from baseline). The adjusted odds ratio was controlled for both procedure and patient characteristics. Results: After implementation of capnography, a significant reduction (43.2%, p ≤ 0.05) in adverse events was observed: 147 adverse events occurred during 666 procedures without capnography compared with 93 adverse events that occurred during 735 procedures with capnography. The adjusted odds ratio for the occurrence of the target adverse events was 0.57 (95% CI: 0.42-0.77). Multivariable linear regression indicated that capnography was a significant predictor (p 0.001) of reduced adverse events. Conclusion: These results suggest improved patient safety following capnography implementation.
dc.languageen
dc.publisherFrontiers Media SA
dc.subjectMedicine
dc.subjectsafe sedation practice
dc.subjectmonitoring
dc.subjectrespiratory compromise
dc.subjectendoscopy
dc.subjectbronchoscopy
dc.subjectpatient safety
dc.titleService Evaluation of the Impact of Capnography on the Safety of Procedural Sedation.
dc.typeArticle
dc.date.updated2022-05-20T10:00:06Z
prism.publicationNameFront Med (Lausanne)
prism.volume9
dc.identifier.doi10.17863/CAM.84752
dcterms.dateAccepted2022-04-15
rioxxterms.versionofrecord10.3389/fmed.2022.867536
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.identifier.eissn2296-858X
cam.issuedOnline2022-05-06


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