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dc.contributor.authorDay, Daphne
dc.contributor.authorGrech, Lisa
dc.contributor.authorNguyen, Mike
dc.contributor.authorBain, Nathan
dc.contributor.authorKwok, Alastair
dc.contributor.authorHarris, Sam
dc.contributor.authorChau, Hieu
dc.contributor.authorChan, Bryan
dc.contributor.authorBlennerhassett, Richard
dc.contributor.authorNott, Louise
dc.contributor.authorHamad, Nada
dc.contributor.authorTognela, Annette
dc.contributor.authorHoffman, David
dc.contributor.authorMcCartney, Amelia
dc.contributor.authorWebber, Kate
dc.contributor.authorWong, Jennifer
dc.contributor.authorUnderhill, Craig
dc.contributor.authorSillars, Brett
dc.contributor.authorWinkel, Antony
dc.contributor.authorSavage, Mark
dc.contributor.authorLoe, Bao Sheng
dc.contributor.authorFreeman, Daniel
dc.contributor.authorSegelov, Eva
dc.contributor.authorOn Behalf Of The Canvaccs Diabvaccs And Msvaccs Investigators
dc.date.accessioned2022-05-30T11:04:19Z
dc.date.available2022-05-30T11:04:19Z
dc.date.issued2022-05-26
dc.identifier.issn2076-393X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337592
dc.description.abstractAs COVID-19 vaccinations became available and were proven effective in preventing serious infection, uptake amongst individuals varied, including in medically vulnerable populations. This cross-sectional multi-site study examined vaccine uptake, hesitancy, and explanatory factors amongst people with serious and/or chronic health conditions, including the impact of underlying disease on attitudes to vaccination. A 42-item survey was distributed to people with cancer, diabetes, or multiple sclerosis across ten Australian health services from 30 June to 5 October 2021. The survey evaluated sociodemographic and disease-related characteristics and incorporated three validated scales measuring vaccine hesitancy and vaccine-related beliefs generally and specific to their disease: the Oxford COVID-19 Vaccine Hesitancy Scale, the Oxford COVID-19 Vaccine Confidence and Complacency Scale and the Disease Influenced Vaccine Acceptance Scale-Six. Among 4683 participants (2548 [54.4%] female, 2108 [45.0%] male, 27 [0.6%] other; mean [SD] age, 60.6 [13.3] years; 3560 [76.0%] cancer, 842 [18.0%] diabetes, and 281 [6.0%] multiple sclerosis), 3813 (81.5%) self-reported having at least one COVID-19 vaccine. Unvaccinated status was associated with younger age, female sex, lower education and income, English as a second language, and residence in regional areas. Unvaccinated participants were more likely to report greater vaccine hesitancy and more negative perceptions toward vaccines. Disease-related vaccine concerns were associated with unvaccinated status and hesitancy, including greater complacency about COVID-19 infection, and concerns relating to vaccine efficacy and impact on their disease and/or treatment. This highlights the need to develop targeted strategies and education about COVID-19 vaccination to support medically vulnerable populations and health professionals.
dc.languageen
dc.publisherMDPI AG
dc.subjectCOVID-19
dc.subjectvaccine hesitancy
dc.subjectcancer
dc.subjectdiabetes
dc.subjectmultiple sclerosis
dc.titleSerious Underlying Medical Conditions and COVID-19 Vaccine Hesitancy: A Large Cross-Sectional Analysis from Australia.
dc.typeArticle
dc.date.updated2022-05-30T11:04:18Z
prism.issueIdentifier6
prism.publicationNameVaccines (Basel)
prism.volume10
dc.identifier.doi10.17863/CAM.85002
dcterms.dateAccepted2022-05-23
rioxxterms.versionofrecord10.3390/vaccines10060851
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidDay, Daphne [0000-0001-8262-2441]
dc.contributor.orcidNguyen, Mike [0000-0003-3044-1707]
dc.contributor.orcidBain, Nathan [0000-0002-3320-8444]
dc.contributor.orcidMcCartney, Amelia [0000-0003-0411-0736]
dc.contributor.orcidWebber, Kate [0000-0003-4350-0884]
dc.contributor.orcidWinkel, Antony [0000-0002-6100-4764]
dc.contributor.orcidSegelov, Eva [0000-0002-4410-6144]
dc.identifier.eissn2076-393X
cam.issuedOnline2022-05-26


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