Modern imaging in Cushing's disease.
Springer Science and Business Media LLC
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Bashari, W., Gillett, D., MacFarlane, J., Powlson, A., Kolias, A., Mannion, R., Scoffings, D., et al. (2022). Modern imaging in Cushing's disease.. Pituitary https://doi.org/10.1007/s11102-022-01236-w
Management of Cushing's disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30-50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when using standard clinical sequences. In this context, alternative MR protocols [e.g. 3D gradient (recalled) echo, with acquisition of volumetric data] may allow detection of tumors that have not been previously visualized. The use of hybrid molecular imaging (e.g. 11C-methionine positron emission tomography coregistered with volumetric MRI) has also been proposed as an additional modality for localizing microadenomas.
National Institute for Health Research (NIHRDH-IS-BRC-1215-20014)
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External DOI: https://doi.org/10.1007/s11102-022-01236-w
This record's URL: https://www.repository.cam.ac.uk/handle/1810/337694
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