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dc.contributor.authorFurse, Samuel
dc.date.accessioned2022-06-07T08:11:51Z
dc.date.available2022-06-07T08:11:51Z
dc.date.issued2022-05-31
dc.date.submitted2022-01-08
dc.identifier.others11306-022-01884-w
dc.identifier.other1884
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337765
dc.description.abstractAbstract: Much evidence for diabetes mellitus being associated with dysregulated lipid metabolism has been accrued from studies using blood plasma. However, the systemic dysregulation these results point to is not understood. This study used Lipid Traffic Analysis on data from a mouse model of diabetes to test the hypothesis that the systemic control of lipid metabolism differed in a model of diabetes. This provided eidence for changes in the systemic control of both triglyceride and phospholipid metabolism that were not attributable to dietary intake. This supports the conclusion that diabetes is a systemic condition associated with dysregulated lipid metabolism through several pathways.
dc.languageen
dc.publisherSpringer US
dc.subjectShort Communication
dc.subjectLipid traffic analysis
dc.subjectT2DM
dc.subjectLipid metabolism
dc.titleLipid metabolism is dysregulated in a mouse model of diabetes
dc.typeOther
dc.date.updated2022-06-07T08:11:51Z
prism.issueIdentifier6
prism.publicationNameMetabolomics
prism.volume18
dc.identifier.doi10.17863/CAM.85174
dcterms.dateAccepted2022-04-01
rioxxterms.versionofrecord10.1007/s11306-022-01884-w
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidFurse, Samuel [0000-0003-4267-2051]
dc.identifier.eissn1573-3890
pubs.funder-project-idBiotechnology and Biological Sciences Research Council (BB/M027252/1, BB/T014210/1)


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