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dc.contributor.authorLund, Ken
dc.contributor.authorLarsen, Michael Due
dc.contributor.authorKnudsen, Torben
dc.contributor.authorKjeldsen, Jens
dc.contributor.authorNielsen, Rasmus Gaardskær
dc.contributor.authorBrage, Soren
dc.contributor.authorNørgård, Bente Mertz
dc.date.accessioned2022-06-07T15:00:58Z
dc.date.available2022-06-07T15:00:58Z
dc.date.issued2022-06-07
dc.date.submitted2021-10-04
dc.identifier.issn1471-230X
dc.identifier.others12876-022-02358-y
dc.identifier.other2358
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337876
dc.descriptionFunder: The Region of Southern Denmark
dc.descriptionFunder: The University of Southern Denmark
dc.descriptionFunder: The Beckett Foundation
dc.descriptionFunder: The Odense University Hospital Chief Physician Foundation
dc.description.abstractOBJECTIVES: Physical activity in paediatric and young adult patients suffering from inflammatory bowel disease (IBD) may play an important role in the overall health status. However, physical activity in these patients has not been reported using objective methods. We aimed to describe accelerometry-measured physical activity levels in paediatric and young adult IBD patients with either ulcerative colitis (UC) or Crohn's disease (CD). METHODS: We recruited Danish patients with IBD aged 10-20 years in clinical remission and with a faecal calprotectin below 200 µg/mg. Physical activity was assessed using tri-axial wrist accelerometry over seven days and quantified using the activity-related acceleration derived as the conventional Euclidian Norm Minus One (ENMO) metric expressed in milli-gravity units (mg). Time spent in Moderate-to-Vigorous Physical Activity (MVPA) was classified as ENMO > 210 mg in 5 s epoch resolution (unbouted). RESULTS: We included 61 patients with a median age of 17 years [Inter Quartile Range, IQR 14-19]. The total volume of activity expressed as average acceleration (ENMO) per day was 31.5 mg (95% CI 29.1-33.9). Time spent in unbouted MVPA was 32 min per day (95% CI 26-37). There was no significant difference in activity volume between patients with UC to patients with CD, the adjusted linear regression coefficient was - 1.7 mg (95% CI -6.2-2.7). Activity volume was higher for males (36.2 mg, 95% CI 31.9-40.5) than for females (27.8 mg, 95% CI 25.6-30.0), and younger patients were more active than older patients; Activity volume in 10-13 year olds was 37.2 mg (95% CI 28.6-45.7), whereas it was 28.5 mg (95% CI 25.2-31.7) for those aged 18-20 years. CONCLUSIONS: We collected tri-axial accelerometry in young patients with IBD in clinical remission, and described their level of physical activity by the conventional ENMO measure. We found no statistically significant difference in patients with UC compared to patients with CD. The volume of physical activity was higher in males compared to females, and inversely associated with age.
dc.languageen
dc.publisherSpringer Science and Business Media LLC
dc.subjectResearch
dc.subjectPhysical activity
dc.subjectAccelerometers
dc.subjectCrohn’s disease
dc.subjectUlcerative colitis
dc.subjectPaediatrics
dc.titlePhysical activity measured by accelerometry in paediatric and young adult patients with inflammatory bowel disease.
dc.typeArticle
dc.date.updated2022-06-07T15:00:58Z
prism.issueIdentifier1
prism.publicationNameBMC Gastroenterol
prism.volume22
dc.identifier.doi10.17863/CAM.85282
dcterms.dateAccepted2022-05-25
rioxxterms.versionofrecord10.1186/s12876-022-02358-y
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidLund, Ken [0000-0002-3959-2926]
dc.contributor.orcidLarsen, Michael Due [0000-0002-0623-2481]
dc.contributor.orcidKnudsen, Torben [0000-0003-0726-0115]
dc.contributor.orcidKjeldsen, Jens [0000-0001-8148-6572]
dc.contributor.orcidBrage, Soren [0000-0002-1265-7355]
dc.contributor.orcidNørgård, Bente Mertz [0000-0002-9514-3033]
dc.identifier.eissn1471-230X
pubs.funder-project-idCambridge University Hospitals NHS Foundation Trust (CUH) (146281)
pubs.funder-project-idMRC (MC_UU_00006/4)
pubs.funder-project-idNational Institute for Health Research (NIHRDH-IS-BRC-1215-20014)
cam.issuedOnline2022-06-07


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