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dc.contributor.authorLiu, Qiu‐Luo
dc.contributor.authorLi, Xi
dc.contributor.authorChen, Hai‐Ning
dc.date.accessioned2022-06-29T19:50:27Z
dc.date.available2022-06-29T19:50:27Z
dc.date.issued2022-06
dc.date.submitted2022-03-21
dc.identifier.issn2769-6448
dc.identifier.othermog25
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/338607
dc.description.abstractAbstract: In the era of precision medicine, the selection of cancer treatment relies increasingly on the identification of genomic alterations; however, it is not yet clear how frequently genomic profiling should be performed over the disease course of a patient with metastatic cancer. A large‐scale study investigates the genomic evolution of cancer metastases under therapeutic pressure and finds that the actionable genome has remained relatively stable. The findings support the sufficiency of a single biopsy of cancer metastasis for therapeutic decision‐making.
dc.languageen
dc.publisherWiley
dc.subjectHIGHLIGHT
dc.titleGenomic evolution of cancer metastasis under therapeutic pressure
dc.typeArticle
dc.date.updated2022-06-29T19:50:27Z
prism.issueIdentifier1
prism.publicationNameMedComm – Oncology
prism.volume1
dc.identifier.doi10.17863/CAM.86020
dcterms.dateAccepted2022-04-06
rioxxterms.versionofrecord10.1002/mog2.5
rioxxterms.versionAO
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidChen, Hai‐Ning [0000-0003-0104-8498]
dc.identifier.eissn2769-6448
pubs.funder-project-idNational Natural Science Foundation of China (82073246)
pubs.funder-project-idSichuan Science and Technology Programme (2022JDRC0049)
cam.issuedOnline2022-06-29


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