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dc.contributor.authorXu, Yufan
dc.contributor.authorZhu, Hongjia
dc.contributor.authorDenduluri, Akhila
dc.contributor.authorOu, Yangteng
dc.contributor.authorErkamp, Nadia A
dc.contributor.authorQi, Runzhang
dc.contributor.authorShen, Yi
dc.contributor.authorKnowles, Tuomas PJ
dc.date.accessioned2022-07-05T22:00:08Z
dc.date.available2022-07-05T22:00:08Z
dc.date.issued2022-08
dc.date.submitted2022-01-10
dc.identifier.citationSmall, article-number 2200180
dc.identifier.issn1613-6810
dc.identifier.othersmll202200180
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/338823
dc.descriptionFunder: Jardine Foundation
dc.descriptionFunder: Trinity College Cambridge
dc.descriptionFunder: China Scholarship Council; Id: http://dx.doi.org/10.13039/501100004543
dc.descriptionFunder: Trinity College Krishnan‐Ang Studentship
dc.descriptionFunder: Honorary Trinity‐Henry Barlow Scholarship
dc.descriptionFunder: Newman Foundation
dc.descriptionFunder: European Research Council; Id: http://dx.doi.org/10.13039/501100000781
dc.description.abstractThe emerging applications of hydrogel materials at different length scales, in areas ranging from sustainability to health, have driven the progress in the design and manufacturing of microgels. Microgels can provide miniaturized, monodisperse, and regulatable compartments, which can be spatially separated or interconnected. These microscopic materials provide novel opportunities for generating biomimetic cell culture environments and are thus key to the advances of modern biomedical research. The evolution of the physical and chemical properties has, furthermore, highlighted the potentials of microgels in the context of materials science and bioengineering. This review describes the recent research progress in the fabrication, characterization, and applications of microgels generated from biomolecular building blocks. A key enabling technology allowing the tailoring of the properties of microgels is their synthesis through microfluidic technologies, and this paper highlights recent advances in these areas and their impact on expanding the physicochemical parameter space accessible using microgels. This review finally discusses the emerging roles that microgels play in liquid-liquid phase separation, micromechanics, biosensors, and regenerative medicine.
dc.languageen
dc.publisherWiley
dc.subjectReview
dc.subjectReviews
dc.subject3D cell cultures
dc.subjectbiomolecules
dc.subjectbiosensing
dc.subjectcharacterization
dc.subjectfabrication
dc.subjectliquid–liquid phase separation
dc.subjectmicrogels
dc.subjectmicromechanics
dc.titleRecent Advances in Microgels: From Biomolecules to Functionality.
dc.typeArticle
dc.date.updated2022-07-05T22:00:08Z
prism.publicationNameSmall
dc.identifier.doi10.17863/CAM.86230
dcterms.dateAccepted2022-03-22
rioxxterms.versionofrecord10.1002/smll.202200180
rioxxterms.versionAO
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidXu, Yufan [0000-0002-7498-3009]
dc.contributor.orcidZhu, Hongjia [0000-0001-7707-353X]
dc.contributor.orcidErkamp, Nadia A [0000-0003-4095-2105]
dc.contributor.orcidQi, Runzhang [0000-0002-7805-6501]
dc.contributor.orcidShen, Yi [0000-0002-0456-0385]
dc.contributor.orcidKnowles, Tuomas PJ [0000-0002-7879-0140]
dc.identifier.eissn1613-6829
pubs.funder-project-idEuropean Research Council (337969)
cam.issuedOnline2022-07-05


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