Show simple item record

dc.contributor.authorForsyth, Faye
dc.contributor.authorMulrennan, Sandra
dc.contributor.authorBurt, Jenni
dc.contributor.authorHartley, Peter
dc.contributor.authorKuhn, Isla
dc.contributor.authorLin, Helen
dc.contributor.authorMant, Jonathan
dc.contributor.authorTan, Sapphire
dc.contributor.authorZhang, Roy
dc.contributor.authorDeaton, Christi
dc.date.accessioned2022-07-06T13:23:18Z
dc.date.available2022-07-06T13:23:18Z
dc.date.issued2022-07-11
dc.identifier.issn1474-5151
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/338840
dc.descriptionAim: To determine what dietary interventions have been tested in HFpEF, the modulation method and outcomes employed and to summarise any evidence for benefit. Methods and Results: We performed key word searches in five bibliographic databases from 2001 to 2021, to identify randomised or experimental dietary interventions tested in HFpEF or mixed HF samples. Study characteristics were summarised according to PICO (population, intervention, comparator, outcome) categories and intervention complexity was assessed Twenty-five clinical investigations were retrieved; only ten (40%) were conducted exclusively in HFpEF; the remainder enrolled mixed HF samples. Most studies employed either highly tailored prescribed diets (n=12, 48%) or dietary supplementation (n=10, 40%) modalities. Dietary pattern interventions (n=3, 12%) are less well represented in the literature.
dc.description.abstractAIM: To determine what dietary interventions have been tested in HFpEF, the modulation method and outcomes employed and to summarise any evidence for benefit. METHODS AND RESULTS: We performed key word searches in five bibliographic databases from 2001 to 2021, to identify randomised or experimental dietary interventions tested in HFpEF or mixed HF samples. Study characteristics were summarised according to PICO (population, intervention, comparator, outcome) categories and intervention complexity was assessed Twenty-five clinical investigations were retrieved; only ten (40%) were conducted exclusively in HFpEF; the remainder enrolled mixed HF samples. Most studies employed either highly tailored prescribed diets (n = 12, 48%) or dietary supplementation (n = 10, 40%) modalities. Dietary pattern interventions (n = 3, 12%) are less well represented in the literature. CONCLUSIONS: Heterogeneity made pooling studies challenging. Better reporting of baseline characteristics and use of standardised HF lexicon would ensure greater confidence in interpretation of studies involving mixed HF populations. The field would benefit greatly from explicit reporting of the biological mechanism of action (e.g. the causal pathway) that an intervention is designed to modulate so that studies can be synthesised via their underlying mechanism of action by which diet may affect HF. An extension of the current set of core outcomes proposed by the European Society of Cardiology Heart Failure Association would ensure dietary clinical endpoints are more consistently defined and measured.
dc.description.sponsorshipEvelyn Trust, Bart's Charity
dc.formatR for datascience, covidence, Rayyan - all referenced within text
dc.publisherOxford University Press (OUP)
dc.rightsAll Rights Reserved
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserved
dc.subjectheart failure
dc.titleWhat dietary interventions have been tested in Heart Failure with Preserved Ejection Fraction? A systematic scoping review.
dc.typeArticle
dc.publisher.departmentDepartment of Public Health and Primary Care
dc.date.updated2022-07-05T08:27:27Z
prism.publicationNameEur J Cardiovasc Nurs
dc.identifier.doi10.17863/CAM.86175
dcterms.dateAccepted2022-07-05
rioxxterms.versionofrecord10.1093/eurjcn/zvac062
rioxxterms.versionAM
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
datacite.contributor.supervisorDeaton, Christi
dcterms.formatword
dc.contributor.orcidForsyth, Faye [0000-0003-2107-3690]
dc.contributor.orcidBurt, Jenni [0000-0002-0037-274X]
dc.contributor.orcidHartley, Peter [0000-0002-1033-5897]
dc.contributor.orcidKuhn, Isla [0000-0002-2879-4020]
dc.contributor.orcidLin, Helen [0000-0001-8491-558X]
dc.contributor.orcidMant, Jonathan [0000-0002-9531-0268]
dc.contributor.orcidDeaton, Christi [0000-0003-3209-0752]
dc.identifier.eissn1873-1953
rioxxterms.typeJournal Article/Review
pubs.funder-project-idEvelyn Trust (21/15)
cam.issuedOnline2022-07-11
cam.orpheus.success2022-08-12: Embargo updated
cam.orpheus.counter3
cam.depositDate2022-07-05
pubs.licence-identifierapollo-deposit-licence-2-1
pubs.licence-display-nameApollo Repository Deposit Licence Agreement
rioxxterms.freetoread.startdate2023-07-11


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record