Research data supporting "Human mesenchymal stem cells and derived extracellular vesicles reduce sensory neuron hyperexcitability and pain-related behaviors in a mouse model of osteoarthritis"
Description
Each file is a Prism file containing all the raw and analysed data that underpins each figure of the paper and the files are accordingly named.
msFig1_behavioral, Figure 1- Behavioural data
msFig2_histology, Figure 2 - Histology data
OARSI histological scoring for DMM mice, explanation how histology was scored in Figure 2
msFig3_ephys, Figure 3, DRG neurone electrophysiology data from osteoarthritis model mice
msFig4_coculture_ephys, Figure 4, DRG neurone electrophysiology data from co-culture experiments
supplmentary figures, Raw data for all supplementary figure files
A full explanation of methods, analysis and interpretation is provided in the paper.
Format
Files accessible with Graphpad Prism and Microsoft Word
Keywords
Inflammation, Pain
Relationships
Publication Reference: https://www.repository.cam.ac.uk/handle/1810/340515
Sponsorship
This work was supported by funding from Versus Arthritis (RG21973) to E.S.J.S and Horizon 2020 (RG90905) and Innovate UK (RG87266) to F.M.D.H. L.A.P was supported by the University of Cambridge BBSRC Doctoral Training Program (BB/M011194/1)
Funder references
Arthritis Research UK (11600/21973)
BBSRC (1943916)
Embargo Lift Date
2100-01-01
Identifiers
This record's DOI: https://doi.org/10.17863/CAM.81339
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
Statistics
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Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)