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Production, characterisation and uses of antibodies to the insulin secretory granule membrane


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Type

Thesis

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Authors

Grimaldi, Keith Anthony 

Abstract

The aim of the work described in this thesis was to prepare and characterise a library of monoclonal antibodies that recognise antigens present in the insulin secretory granule membrane. These were to be used in a study of the composition, biosynthesis and turnover of the secretory granule membrane.

Description

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Date

Advisors

Siddle, Ken
Hutton, John

Keywords

Monoclonal antibodies, Antigens, Insulin secretory granule membrane

Qualification

Doctor of Philosophy (PhD)

Awarding Institution

University of Cambridge