Research data in support of: "Influence of hydrophobic moieties on the crystallization of amphiphilic DNA nanostructures"
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Repository DOI
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Type
Dataset
Change log
Authors
Brady, Ryan
Leathers, Adrian
Kotar, Jurij
Di Michele, Lorenzo
Description
Data supporting the manuscript titled: "Influence of hydrophobic moieties on the crystallization of amphiphilic DNA nanostructures". The uploaded dataset contains:
- images of agarose gels with non-functionalized DNA motifs,
- DLS data / images of agarose gels with DNA micelles,
- SAXS data of DNA crystals,
- bright-field images of DNA crystals,
- confocal micrographs of DNA crystals loaded with antibiotic molecules.
Version
Software / Usage instructions
TIF files can be opened and analysed using most of the available image visualisation/analysis software programs (examples include ImageJ and Matlab).
CSV files can be directly opened with Microsoft Excel or imported into any text data analysis software program (for example, Matlab or Jupyter Notebook).
LIF files containing images with all the metadata, for example, pixel size, can be read in selected image visualisation/analysis software programs (ImageJ, Python or Matlab) using the respective Bioformats plug-in/library.
NXS files containing diffraction data can be opened with free software called DAWN, available on the Diamond Light source website (https://www.diamond.ac.uk/Science/Computing/Data-Analysis.html).
TXT files including detailed description of the data can be opened using Notepad.
Keywords
Cargo encapsulation, DNA crystals, DNA nanotechnology, Synthetic biology
Publisher
Sponsorship
EPSRC (2127174)
Engineering and Physical Sciences Research Council (2127174)
Royal Society (UF160152)
Royal Society (via Imperial College London) (RGF/R1/180043)
Royal Society (RGF/R1/180043)
Engineering and Physical Sciences Research Council (2127174)
Royal Society (UF160152)
Royal Society (via Imperial College London) (RGF/R1/180043)
Royal Society (RGF/R1/180043)
L.D.M. acknowledges support from a Royal Society University Research Fellowship (UF160152) and from the European Research Council (ERC) under the Horizon 2020 Research and Innovation Programme (ERC-STG No 851667 - NANOCELL). A.L. and L.D.M. acknowledge support from a Royal Society Research Grant for Research Fellows (RGF/R1/180043). M.W. acknowledges support from the Engineering and Physical Sciences Research Council (EPSRC) and the Department of Physics at the University of Cambridge (the McLatchie Trust fund). The authors acknowledge Diamond Light Source for providing synchrotron beamtime (SM24537, SM29072).