Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study.

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Wu, Yu-Tzu 
Prina, A Matthew 
Jones, Andy 
Barnes, Linda E 
Matthews, Fiona E 

This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75-79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80-84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old.

Land use mix, Mortality, Neighbourhood, Older people, Aged, Aged, 80 and over, Aging, England, Environment Design, Female, Humans, Interviews as Topic, Male, Mortality, Proportional Hazards Models, Registries, Wales, Walking
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Health Place
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Elsevier BV
Medical Research Council (G9901400)
Department of Health (via National Institute for Health Research (NIHR)) (unknown)
Medical Research Council (G0601022)
ESRC (via Bangor University) (RES-060-25-0060)
Economic and Social Research Council (ES/G007462/1)
Medical Research Council (MR/K023187/1)
Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) was funded by the Department of Health and the Medical Research Council, [Grant number G9901400]; Fiona E Matthews and Matthew Prina are supported by the Medical Research Council [Grant number U105292687 & MR/K021907/1]; Yu-Tzu Wu received a PhD scholarship from Cambridge Trust, University of Cambridge. We thank the participants, their families, general practitioners and their staff, and the primary care trusts for their cooperation and support.