Comparative Connectomics.

Accepted version
Repository DOI

Type
Article
Change log
Authors
van den Heuvel, Martijn P 
Bullmore, Edward T 
Sporns, Olaf 
Abstract

We introduce comparative connectomics, the quantitative study of cross-species commonalities and variations in brain network topology that aims to discover general principles of network architecture of nervous systems and the identification of species-specific features of brain connectivity. By comparing connectomes derived from simple to more advanced species, we identify two conserved themes of wiring: the tendency to organize network topology into communities that serve specialized functionality and the general drive to enable high topological integration by means of investment of neural resources in short communication paths, hubs, and rich clubs. Within the space of wiring possibilities that conform to these common principles, we argue that differences in connectome organization between closely related species support adaptations in cognition and behavior.

Description
Keywords
Brain, Brain Mapping, Cognition, Communication, Connectome, Nerve Net, Species Specificity
Journal Title
Trends Cogn Sci
Conference Name
Journal ISSN
1364-6613
1879-307X
Volume Title
20
Publisher
Elsevier BV
Sponsorship
We thank Lianne Scholtens, Jim Rilling, Tom Schoenemann for discussions and comments. MPvdH was supported by a VENI (# 451-12-001) grant from the Netherlands Organization for Scientific Research (NWO) and a Fellowship of MQ.