I review recent advances in the calculation of higher-order soft-gluon corrections for a variety of QCD, Higgs, and SUSY processes in hadron colliders. A unified approach and master formulas for next-to-next-to-leading order soft and virtual corrections are discussed. I present some applications of the formalism to top quark pair production at the Tevatron and the LHC, top production via anomalous couplings in flavor-changing neutral-current processes, W boson hadroproduction at large transverse momentum, and charged Higgs production at the LHC.