The paper contributes to the literature focusing on the role of ideas, practices and human capital in pre-modern European economic development. It argues that studying the spread of Hindu- Arabic numerals among European practitioners allows to open up a perspective on a progressive transmission of useful knowledge from the commercial revolution to the early modern period. The analysis is based on an original database recording detailed information on over 1200 texts, both manuscript and printed. This database provides the most detailed reconstruction available of the European tradition of practical arithmetic from the late 13th to the end of the 16th century. It can be argued that this is the tradition which drove the adoption of Hindu-Arabic numerals in Europe. The dataset is analysed with statistical and spatial tools. Since the spread of these texts is grounded on inland patterns, the evidence suggests that a continuous transmission of useful knowledge may have played a role during the shift of the core of European trade from the Mediterranean to the Atlantic.