Epigenetics and metabolism in 2014: Metabolic programming--knowns, unknowns and possibilities.
Change log
Authors
Ozanne, Susan E
Abstract
Studies published in 2014 have helped in our understanding of the epigenetic mechanisms by which suboptimal nutritional exposures during in utero development are transmitted to subsequent generations through both the maternal and paternal line. Advances include identification of common loci that are vulnerable to in utero under-nutrition and over-nutrition as well as those that occur tissue-wide.
Description
Keywords
Diabetes Mellitus, Type 2, Epigenesis, Genetic, Humans, Models, Biological
Journal Title
Nat Rev Endocrinol
Conference Name
Journal ISSN
1759-5029
1759-5037
1759-5037
Volume Title
11
Publisher
Nature Publishing Group
Publisher DOI
Sponsorship
British Heart Foundation (None)
British Heart Foundation (None)
Medical Research Council (MC_UU_12012/4)
Diabetes UK (None)
Medical Research Council (MC_PC_12012)
British Heart Foundation (None)
Medical Research Council (MC_UU_12012/4)
Diabetes UK (None)
Medical Research Council (MC_PC_12012)
S. E. Ozanne is receiving grants from the British Heart Foundation
(PG/13/46/30329), Diabetes UK (12/0004508), the European Union (Seventh
Framework Programme EarlyNutrition under Grant agreement no. 289346) and Medical Research Council (MRC_MC_UU_12012/4).