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Are Electronic Cigarettes an Effective Aid to Smoking Cessation or Reduction Among Vulnerable Groups? A Systematic Review of Quantitative and Qualitative Evidence.

cam.issuedOnline2018-03-28
dc.contributor.authorGentry, Sarah
dc.contributor.authorForouhi, Nita G
dc.contributor.authorNotley, Caitlin
dc.contributor.orcidGentry, Sarah [0000-0002-0805-0200]
dc.contributor.orcidForouhi, Nita [0000-0002-5041-248X]
dc.date.accessioned2018-09-10T22:15:33Z
dc.date.available2018-09-10T22:15:33Z
dc.date.issued2019-04-17
dc.description.abstractINTRODUCTION: Smoking prevalence remains high in some vulnerable groups, including those who misuse substances, have a mental illness, are homeless, or are involved with the criminal justice system. E-cigarette use is increasing and may support smoking cessation/reduction. METHODS: Systematic review of quantitative and qualitative data on the effectiveness of e-cigarettes for smoking cessation/reduction among vulnerable groups. Databases searched were MEDLINE, EMBASE, PsychINFO, CINAHL, ASSIA, ProQuest Dissertations and Theses, and Open Grey. Narrative synthesis of quantitative data and thematic synthesis of qualitative data. RESULTS: 2628 records and 46 full texts were screened; 9 studies were identified for inclusion. Due to low quality of evidence, it is uncertain whether e-cigarettes are effective for smoking cessation in vulnerable populations. A moderate quality study suggested that e-cigarettes were as effective as nicotine replacement therapy. Four studies suggested significant smoking reduction; however, three were uncontrolled and had sample sizes below 30. A prospective cohort study found no differences between e-cigarette users and nonusers. No significant adverse events and minimal side effects were identified. Qualitative thematic synthesis revealed barriers and facilitators associated with each component of the COM-B (capability, opportunity, motivation, and behavior) model, including practical barriers; perceptions of effectiveness for cessation/reduction; design features contributing to automatic and reflective motivation; smoking bans facilitating practical opportunity; and social connectedness increasing social opportunity. CONCLUSION: Further research is needed to identify the most appropriate device types for practicality and safety, level of support required in e-cigarette interventions, and to compare e-cigarettes with current best practice smoking cessation support among vulnerable groups. IMPLICATIONS: Smoking prevalence among people with mental illness, substance misuse, homelessness, or criminal justice system involvement remains high. E-cigarettes could support cessation. This systematic review found limited quantitative evidence assessing effectiveness. No serious adverse events were identified. Qualitative thematic synthesis revealed barriers and facilitators mapping to each component of the COM-B (capability, opportunity, motivation, and behavior) model, including practical barriers; perceived effectiveness; design features contributing to automatic and reflective motivation; smoking bans facilitating practical opportunity; and social connectedness increasing social opportunity. Further research should consider appropriate devices for practicality and safety, concurrent support, and comparison with best practice smoking cessation support.
dc.format.mediumPrint
dc.identifier.doi10.17863/CAM.27388
dc.identifier.eissn1469-994X
dc.identifier.issn1462-2203
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/280023
dc.languageeng
dc.language.isoeng
dc.publisherOxford University Press (OUP)
dc.publisher.urlhttp://dx.doi.org/10.1093/ntr/nty054
dc.subjectElectronic Nicotine Delivery Systems
dc.subjectHumans
dc.subjectProspective Studies
dc.subjectQualitative Research
dc.subjectSmoking Cessation
dc.subjectSmoking Reduction
dc.subjectText Messaging
dc.subjectTobacco Smoking
dc.subjectVaping
dc.subjectVulnerable Populations
dc.titleAre Electronic Cigarettes an Effective Aid to Smoking Cessation or Reduction Among Vulnerable Groups? A Systematic Review of Quantitative and Qualitative Evidence.
dc.typeArticle
dcterms.dateAccepted2018-03-27
prism.endingPage616
prism.issueIdentifier5
prism.publicationDate2019
prism.publicationNameNicotine Tob Res
prism.startingPage602
prism.volume21
pubs.funder-project-idMedical Research Council (MC_UU_12015/5)
rioxxterms.licenseref.startdate2019-04
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review
rioxxterms.versionAM
rioxxterms.versionofrecord10.1093/ntr/nty054

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