A pilot study to examine association of BMI with functional class and 6 min walk distance in idiopathic and heritable PAH: Possible association with estrogen metabolism.
Published version
Peer-reviewed
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Repository DOI
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Authors
Pandya, Divya
Swietlik, Emilia M
Denver, Nina
Mair, Kirsty
Abstract
The hypothesis that a relationship exists between body mass index (BMI), functional class, and 6 min walk distance (6MWD) in Group 1-pulmonary arterial hypertension (PAH) was examined. Analysis of data from the UK National Cohort Study for heritable pulmonary arterial/idiopathic PAH suggests increased BMI is a predictor of worse functional class and shorter 6MWD; increased body-weight in mice and man may be associated with increased estrogen metabolism.
Description
Keywords
estrogen, estrogen metabolites, obesity, pulmonary hypertension, sex
Journal Title
Pulm Circ
Conference Name
Journal ISSN
2045-8932
2045-8940
2045-8940
Volume Title
Publisher
Wiley
Publisher DOI
Sponsorship
British Heart Foundation (None)
Medical Research Council (MR/K020919/1)
British Heart Foundation (None)
British Heart Foundation (None)
British Heart Foundation (SP/18/10/33975)
Medical Research Council (MR/K020919/1)
British Heart Foundation (None)
British Heart Foundation (None)
British Heart Foundation (SP/18/10/33975)