FYPO: the fission yeast phenotype ontology.


Type
Article
Change log
Authors
Harris, Midori A 
Lock, Antonia 
Bähler, Jürg 
Oliver, Stephen G 
Abstract

MOTIVATION: To provide consistent computable descriptions of phenotype data, PomBase is developing a formal ontology of phenotypes observed in fission yeast. RESULTS: The fission yeast phenotype ontology (FYPO) is a modular ontology that uses several existing ontologies from the open biological and biomedical ontologies (OBO) collection as building blocks, including the phenotypic quality ontology PATO, the Gene Ontology and Chemical Entities of Biological Interest. Modular ontology development facilitates partially automated effective organization of detailed phenotype descriptions with complex relationships to each other and to underlying biological phenomena. As a result, FYPO supports sophisticated querying, computational analysis and comparison between different experiments and even between species. AVAILABILITY: FYPO releases are available from the Subversion repository at the PomBase SourceForge project page (https://sourceforge.net/p/pombase/code/HEAD/tree/phenotype_ontology/). The current version of FYPO is also available on the OBO Foundry Web site (http://obofoundry.org/).

Description
Keywords
Biological Ontologies, Databases, Genetic, Gene Ontology, Phenotype, Schizosaccharomyces
Journal Title
Bioinformatics
Conference Name
Journal ISSN
1367-4803
1367-4811
Volume Title
29
Publisher
Oxford University Press (OUP)
Sponsorship
Wellcome Trust (090548/Z/09/Z)