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Modelling pellet size and shape evolution during the breakage stage in spheronisation

Accepted version
Peer-reviewed

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Authors

Whelan-Smith, J 
How, MS 
Rough, SL 
Wang, L 
Wilson, DI 

Abstract

In the breakage stage of extrusion-spheronisation, initially cylindrical extrudates undergo simultaneous breakage and rounding on a rotating friction plate. This sets the starting conditions (number of pellets, size and shape distributions) for the subsequent, lengthy, rounding stage. The simultaneous evolution of pellet size and shape during the initial stages of spheronisation has not been considered in depth. Wang et al. (2021) AIChEJ, 67(6), e17247 investigated the breakage of 2 mm diameter microcrystalline cellulose/water extrudates and modelled the evolution of length using a 1-D population balance model. Here the data (over 17,000 images) were reanalysed and classified by both length and shape (8 shape classes). Their model was extended to 2-D (tracking size and shape), and the data fitted by a combination of optimization approaches. The effect of pellet length on the likelihood of breakage over rounding, and the influence of plate rotation speed and initial number of extrudates, is reported

Description

Keywords

4004 Chemical Engineering, 40 Engineering

Journal Title

Powder Technology

Conference Name

Journal ISSN

0032-5910
1873-328X

Volume Title

Publisher

Elsevier BV
Sponsorship
Sabbatical leave funding for author Dr Mohammed Syahmeer How from Universiti Putra Malaysia is gratefully acknowledged
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