SWATH-MS data of $\textit{Drosophila melanogaster}$ proteome dynamics during embryogenesis


Type
Article
Change log
Authors
Fabre, B 
Nightingale, DJH 
Lilley, KS 
Abstract

Embryogenesis is one of the most important processes in the life of an animal. During this dynamic process, progressive cell division and cellular differentiation are accompanied by significant changes in protein expression at the level of the proteome. However, very few studies to date have described the dynamics of the proteome during the early development of an embryo in any organism. In this dataset, we monitor changes in protein expression across a timecourse of more than 20 h of Drosophila melanogaster embryonic development. Mass-spectrometry data were produced using a SWATH acquisition mode on a Sciex Triple-TOF 6600. A spectral library built in-house was used to analyse these data and more than 1950 proteins were quantified at each embryonic timepoint. The files presented here are a permanent digital map and can be reanalysed to test against new hypotheses. The data have been deposited with the ProteomeXchange Consortium with the dataset identifier PRIDE: PXD0031078.

Description
Keywords
early embryo development, mass-spectrometry, SWATH
Journal Title
Data in Brief
Conference Name
Journal ISSN
2352-3409
2352-3409
Volume Title
9
Publisher
Elsevier
Sponsorship
BBSRC (via University of Manchester) (R116574-LLM)
Biotechnology and Biological Sciences Research Council (BB/L002817/1)
B.F, D.K and D.J.H.N are funded by BBSRC, United Kingdom (Ref: BB/L002817/1).