The challenge of early detection in cancer.
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Pharoah, Paul DP
jats:pTumor growth dynamics and the timing of metastasis impose limits on cancer screening</jats:p>
Early Detection of Cancer, Humans, Neoplasm Metastasis, Neoplasms, Randomized Controlled Trials as Topic
American Association for the Advancement of Science (AAAS)
All rights reserved
Multiple developments in imaging and biomarkers have shown promise as tests for the earlier detection of cancer, but a prerequisite for their success in reducing death from cancer is taking into account heterogeneity of tumour growth kinetics and the relationship between tumour size and metastatic potential.