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Multi‐omics analysis reveals drivers of loss of β‐cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study

Published version
Peer-reviewed

Repository DOI


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Abstract

Aims: Heterogeneity in the rate of β‐cell loss in newly diagnosed type 1 diabetes patients is poorly understood and creates a barrier to designing and interpreting disease‐modifying clinical trials. Integrative analyses of baseline multi‐omics data obtained after the diagnosis of type 1 diabetes may provide mechanistic insight into the diverse rates of disease progression after type 1 diabetes diagnosis.

Description

Publication status: Published


Funder: Innovative Medicine Initiative 2 Joint Undertaking


Funder: European Federation of Pharmaceutical Industries and Associations; doi: http://dx.doi.org/10.13039/100013322


Funder: European Union's Horizon 2020 research and innovation program


Funder: Leona M. and Harry B. Helmsley Charitable Trust; doi: http://dx.doi.org/10.13039/100007028


Funder: JDRF; doi: http://dx.doi.org/10.13039/100022690

Journal Title

Diabetes/Metabolism Research and Reviews

Conference Name

Journal ISSN

1520-7552
1520-7560

Volume Title

40

Publisher

John Wiley and Sons

Rights and licensing

Except where otherwised noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International
Sponsorship
European Commission Horizon 2020 (H2020) Societal Challenges (115797 INNODIA)