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Crossing species boundaries in regenerative neuroscience with rat–mouse brain chimeras

Accepted version
Peer-reviewed

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Authors

Pluchino, stefano 

Abstract

Understanding the inherent complexity of organogenesis, combined with the persistent shortage of organ donors, remains a paramount scientific challenge. Recent advances in chimeric blastocyst technology offer promising solutions. Pioneering studies have successfully generated functional rat-mouse brain chimeras, providing novel insights into brain development and potential regenerative therapies. However, significant technical and ethical hurdles persist.

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Journal Title

Lab Animal

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Journal ISSN

0093-7355
1548-4475

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Publisher

Nature Research

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