Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential.
| cam.issuedOnline | 2016-09-01 | |
| dc.contributor.author | Rubinsztein, DC | |
| dc.contributor.author | Frake, RA | |
| dc.contributor.orcid | Rubinsztein, David [0000-0001-5002-5263] | |
| dc.date.accessioned | 2018-09-11T17:31:58Z | |
| dc.date.available | 2018-09-11T17:31:58Z | |
| dc.date.issued | 2016-12 | |
| dc.description.abstract | On 3 October 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine 'for his discoveries of mechanisms for autophagy'; autophagy being an intracellular degradation pathway that helps maintain cytoplasmic homeostasis. This commentary discusses Ohsumi's Nobel prize-winning work in context, before explaining the clinical relevance of autophagy. | |
| dc.format.medium | ||
| dc.identifier.doi | 10.17863/CAM.27555 | |
| dc.identifier.eissn | 2042-8189 | |
| dc.identifier.issn | 1478-2715 | |
| dc.identifier.uri | https://www.repository.cam.ac.uk/handle/1810/280188 | |
| dc.language | eng | |
| dc.language.iso | eng | |
| dc.publisher | SAGE Publications | |
| dc.subject | Yoshinori Ohsumi | |
| dc.subject | autophagy | |
| dc.subject | yeast genetics | |
| dc.subject | Autophagy | |
| dc.subject | History, 20th Century | |
| dc.subject | Homeostasis | |
| dc.subject | Humans | |
| dc.subject | Medicine | |
| dc.subject | Nobel Prize | |
| dc.subject | Physiology | |
| dc.title | Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential. | |
| dc.type | Article | |
| dcterms.dateAccepted | 2016-11-09 | |
| prism.endingPage | 233 | |
| prism.issueIdentifier | 4 | |
| prism.publicationDate | 2016 | |
| prism.publicationName | J R Coll Physicians Edinb | |
| prism.startingPage | 228 | |
| prism.volume | 46 | |
| rioxxterms.licenseref.startdate | 2016-12 | |
| rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | |
| rioxxterms.type | Journal Article/Review | |
| rioxxterms.version | AM | |
| rioxxterms.versionofrecord | 10.4997/jrcpe.2016.403 |
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