A Platform for SpyCatcher Conjugation to Native Antibodies

Protein-antibody conjugates represent major advancements in targeted therapeutics. However, platforms enabling ‘off-the shelf’ antibody conjugation are seldom reported. The SpyTag/SpyCatcher system, known for its stable isopeptide bond formation, is widely...

Keywords

34 Chemical Sciences, Biotechnology, Women's Health, Breast Cancer, Cancer, Cancer, Generic health relevance

Journal Title

Chemical Science

Journal ISSN

2041-6520
2041-6539

Publisher

Royal Society of Chemistry (RSC)

Publisher DOI

https://doi.org/10.1039/d5sc02286j

Rights and licensing

Except where otherwised noted, this item's license is described as Attribution 4.0 International

Sponsorship

Isaac Newton Trust (22.39(l))
BBSRC (2126305)
Biotechnology and Biological Sciences Research Council (BB/S50757X/1)
EPSRC (EP/W001233/1)

Collections

University of Cambridge Research Outputs (Articles and Conferences)