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Interaction between known risk factors for head and neck cancer and socioeconomic status: the Carolina Head and Neck Cancer Study.

cam.issuedOnline2018-08
dc.contributor.authorStanford-Moore, Gaelen
dc.contributor.authorBradshaw, Patrick T
dc.contributor.authorWeissler, Mark C
dc.contributor.authorZevallos, Jose P
dc.contributor.authorBrennan, Paul
dc.contributor.authorAnantharaman, Devasena
dc.contributor.authorAbedi-Ardekani, Behnoush
dc.contributor.authorOlshan, Andrew F
dc.contributor.orcidStanford-Moore, Gaelen [0000-0002-2247-8000]
dc.date.accessioned2018-11-24T00:30:44Z
dc.date.available2018-11-24T00:30:44Z
dc.date.issued2018-09
dc.description.abstractPrior studies of squamous cell carcinoma of the head and neck (SCCHN) have explored the effect of socioeconomic status (SES) as an independent risk factor; however, none have investigated the interaction of known risk factors with SES. We examined this using the North Carolina Head and Neck Cancer Epidemiology Study, a population-based case-control study. Incident cases of SCCHN from North Carolina between 2002 and 2006 (n = 1,153) were identified and age, sex, and race-matched controls (n = 1,267) were selected from driver license records. SES measures included household income, educational attainment, and health insurance. Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI). Current smoking was more strongly associated with SCCHN among those households making < $20,000/year [OR 5.11 (3.61-6.61)] compared to household incomes > $50,000/year [OR 2.47 (1.69-3.25); p interaction < 0.001]. Current drinking was more strongly associated with SCCHN in household incomes < $20,000 [OR 2.91 (2.05-3.78)] compared to > $50,000/year [1.28 (0.97-1.58); p interaction < 0.001]. Current drinkers with less than high school education or income < $20,000 had nearly threefold odds of never-drinkers in the same SES category [OR 2.91 (2.05-3.78); 2.09 (1.39-2.78), respectively]. Our results suggest that the relationship of smoking and alcohol use may be stronger among those of lower SES.
dc.format.mediumPrint-Electronic
dc.identifier.doi10.17863/CAM.25898
dc.identifier.eissn1573-7225
dc.identifier.issn0957-5243
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285920
dc.languageeng
dc.language.isoeng
dc.publisherSpringer Science and Business Media LLC
dc.publisher.urlhttp://dx.doi.org/10.1007/s10552-018-1062-8
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAlcohol
dc.subjectCase–control studies
dc.subjectEpidemiology
dc.subjectHead and neck cancer
dc.subjectRisk factors
dc.subjectSocioeconomic status
dc.subjectTobacco
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAlcohol Drinking
dc.subjectCarcinoma, Squamous Cell
dc.subjectCase-Control Studies
dc.subjectFemale
dc.subjectHead and Neck Neoplasms
dc.subjectHumans
dc.subjectIncome
dc.subjectLogistic Models
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNorth Carolina
dc.subjectOdds Ratio
dc.subjectOral Health
dc.subjectRisk Factors
dc.subjectSmoking
dc.subjectSocial Class
dc.subjectSquamous Cell Carcinoma of Head and Neck
dc.subjectYoung Adult
dc.titleInteraction between known risk factors for head and neck cancer and socioeconomic status: the Carolina Head and Neck Cancer Study.
dc.typeArticle
dcterms.dateAccepted2018-07-24
prism.endingPage873
prism.issueIdentifier9
prism.publicationDate2018
prism.publicationNameCancer Causes Control
prism.startingPage863
prism.volume29
rioxxterms.licenseref.startdate2018-09
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.typeJournal Article/Review
rioxxterms.versionVoR
rioxxterms.versionofrecord10.1007/s10552-018-1062-8

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