Repository logo
 

HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy

Published version
Peer-reviewed

Repository URI

https://www.repository.cam.ac.uk/handle/1810/336482

Repository DOI

https://doi.org/10.17863/CAM.83900
Thumbnail Image

Files

Published version (4.28 MB)

Type

Article

Change log

Authors

Abstract

HIV-1 infections are most commonly initiated with a single founder virus and are characterized by extensive inter- and intraparticipant genetic diversity. However, existing literature on HIV-1 intrahost population dynamics is largely limited to untreated infections, predominantly in subtype B-infected individuals.

Description

Keywords

antiretroviral resistance, clinical failure, drug resistance evolution, human immunodeficiency virus, Anti-HIV Agents, Anti-Retroviral Agents, Drug Resistance, Viral, HIV Infections, HIV Seropositivity, HIV-1, Humans, Viral Load, Viremia

Journal Title

mBio

Conference Name

Journal ISSN

2150-7511
2150-7511

Volume Title

Publisher

American Society for Microbiology

Publisher DOI

https://doi.org/10.1128/mbio.00269-22

Rights and licensing

Attribution 4.0 International
Except where otherwised noted, this item's license is described as Attribution 4.0 International
Sponsorship
Wellcome Trust (108082/A/15/Z)

Relationships

Is derived from:
https://doi.org/10.1101/2021.04.09.21254592

Collections

University of Cambridge Research Outputs (Articles and Conferences)