Combined optical and electronic sensing of epithelial cells using planar organic transistors.
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Peer-reviewed
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Abstract
A planar, conducting-polymer-based transistor for combined optical and electronic monitoring of live cells provides a unique platform for monitoring the health of cells in vitro. Monitoring of MDCK-I epithelial cells over several days is shown, along with a demonstration of the device for toxicology studies, of use in future drug discovery or diagnostics applications.
Description
Keywords
MDCK cells, barrier tissue, conducting polymers, poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS), tight junctions, Animals, Dogs, Electrical Equipment and Supplies, Epithelial Cells, Madin Darby Canine Kidney Cells, Optical Devices, Polystyrenes, Thiophenes, Transistors, Electronic
Journal Title
Adv Mater
Conference Name
Journal ISSN
0935-9648
1521-4095
1521-4095
Volume Title
26
Publisher
Wiley
Publisher DOI
Sponsorship
European Research Council (258966)