Cholangiocarcinoma presenting as hemobilia and recurrent iron-deficiency anemia: a case report.

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Ahmad, Saif S 
Basheer, Faisal Tm 
Idris, Saad F 
Hariraj, Radhakrishnan 
Mathialagan, Rajarathnam 

INTRODUCTION: Iron-deficiency anemia is a relatively common presenting feature of several gastrointestinal malignancies. However, cholangiocarcinoma has rarely been reported as an underlying cause. The association of cholangiocarcinoma with the rare clinical finding of hemobilia is also highly unusual. To our knowledge, this is the first case report of cholangiocarcinoma presenting with acute hemobilia and chronic iron-deficiency anemia. CASE PRESENTATION: We report the case of a Caucasian, 84-year-old woman presenting with recurrent, severe iron-deficiency anemia who was eventually diagnosed with intra-hepatic cholangiocarcinoma, following an acute episode of hemobilia. A right hepatectomy was subsequently performed with curative intent, and our patient has now fully recovered. CONCLUSION: This is a rare example of hemobilia and chronic iron-deficiency anemia in association with cholangiocarcinoma. We suggest that a diagnosis of cholangiocarcinoma should be considered in patients who present with iron-deficiency anemia of unknown cause, particularly in the presence of abnormal liver function.

1103 Clinical Sciences, Clinical, Clinical Medicine and Science, Cancer, Liver Disease, Liver Cancer, Hematology, Rare Diseases, Digestive Diseases - (Gallbladder), Orphan Drug, Digestive Diseases, 2.1 Biological and endogenous factors
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J Med Case Rep
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Springer Science and Business Media LLC