A new trick for an old lipid.

Published version
Repository URI
https://www.repository.cam.ac.uk/handle/1810/266491
Repository DOI
https://doi.org/10.17863/CAM.11853
Files
Published version (306.22 KB)
Type
Article
Change log
Authors
Abstract

Cholesterol can regulate the Hedgehog signalling pathway by directly binding to a receptor on the cell surface.

Description
Keywords
G-protein coupled receptor, Hedgehog signaling, biochemistry, cholesterol, developmental biology, human, mouse, stem cells, Carrier Proteins, Cell Membrane, Hedgehog Proteins, Humans, Lipids, Receptors, Cell Surface, Receptors, G-Protein-Coupled, Signal Transduction
Journal Title
Elife
Conference Name
Journal ISSN
2050-084X
2050-084X
Volume Title
5
Publisher
eLife Sciences Publications, Ltd
Publisher DOI
https://doi.org/10.7554/eLife.22492
Rights
Attribution 4.0 International (CC BY) Repository logo
Sponsorship
Wellcome Trust (109407/Z/15/Z)
Collections
Scholarly Works - Clinical Biochemistry