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The Sequence Ontology: a tool for the unification of genome annotations.

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Eilbeck, Karen 
Lewis, Suzanna E 
Mungall, Christopher J 
Yandell, Mark 
Stein, Lincoln 


The Sequence Ontology (SO) is a structured controlled vocabulary for the parts of a genomic annotation. SO provides a common set of terms and definitions that will facilitate the exchange, analysis and management of genomic data. Because SO treats part-whole relationships rigorously, data described with it can become substrates for automated reasoning, and instances of sequence features described by the SO can be subjected to a group of logical operations termed extensional mereology operators.



Alternative Splicing, Computational Biology, Databases, Genetic, Documentation, Exons, Genomics, RNA, Messenger, Software Design, Terminology as Topic, Vocabulary, Controlled

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Genome Biol

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Springer Science and Business Media LLC