Synthetic scaffolds help airway cells reach maturity

Synthetic scaffolds help airway cells reach maturity

Published version

Peer-reviewed

Repository URI

https://www.repository.cam.ac.uk/handle/1810/267301

Repository DOI

https://doi.org/10.17863/CAM.13303

Files

Published version (433.46 KB)

Type

Authors

Abstract

Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.

Keywords

developmental biology, human pluripotent stem cells, lung airway, mouse, organoids, scaffolds, stem cells, transplantation, Animals, Cell Differentiation, Humans, Lung, Mice, Organoids, Pluripotent Stem Cells

Journal Title

eLife

Journal ISSN

2050-084X
2050-084X

Volume Title

5

Publisher

eLife Sciences Publications Ltd

Publisher DOI

https://doi.org/10.7554/eLife.21786

Rights and licensing

Attribution 4.0 International

Except where otherwised noted, this item's license is described as Attribution 4.0 International

Sponsorship

Medical Research Council (G0900424)
Wellcome Trust (092096/Z/10/Z)
Wellcome Trust (100677/Z/12/Z)
Wellcome Trust (100677/Z/12/A)
Wellcome Trust (105602/Z/14/Z)
Addenbrooke's Charitable Trust (ACT) (1646)

Collections

Scholarly Works - Cancer Research UK Cambridge Institute