Synthetic scaffolds help airway cells reach maturity

Published version
Repository URI
https://www.repository.cam.ac.uk/handle/1810/267301
Repository DOI
https://doi.org/10.17863/CAM.13303
Files
Published version (433.46 KB)
Type
Article
Change log
Authors
Nikolić, MZ 
Rawlins, EL 
Abstract

Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.

Description
Keywords
developmental biology, human pluripotent stem cells, lung airway, mouse, organoids, scaffolds, stem cells, transplantation, Animals, Cell Differentiation, Humans, Lung, Mice, Organoids, Pluripotent Stem Cells
Journal Title
eLife
Conference Name
Journal ISSN
2050-084X
2050-084X
Volume Title
5
Publisher
eLife Sciences Publications Ltd
Publisher DOI
https://doi.org/10.7554/eLife.21786
Rights
Attribution 4.0 International Repository logo
Sponsorship
Medical Research Council (G0900424)
Wellcome Trust (092096/Z/10/Z)
Wellcome Trust (100677/Z/12/Z)
Wellcome Trust (100677/Z/12/A)
Wellcome Trust (105602/Z/14/Z)
Addenbrooke's Charitable Trust (ACT) (1646)
Collections
Scholarly Works - Cancer Research UK Cambridge Institute