jats:titleAbstract</jats:title>jats:pStable, reproducible, scalable, addressable, and controllable hybrid superconductor–semiconductor (S–Sm) junctions and switches are key circuit elements and building blocks of gate‐based quantum processors. The electrostatic field effect produced by the split gate voltages facilitates the realization of nano‐switches that can control the conductance or current in the hybrid S–Sm circuits based on 2D semiconducting electron systems. Here, a novel realization of large‐scale scalable, and gate voltage controllable hybrid field effect quantum chips is experimentally demonstrated. Each chip contains arrays of split gate field effect hybrid junctions, that work as conductance switches, and are made from Injats:sub0.75</jats:sub>Gajats:sub0.25</jats:sub>As quantum wells integrated with Nb superconducting electronic circuits. Each hybrid junction in the chip can be controlled and addressed through its corresponding source–drain and two global split gate contact pads that allow switching between their (super)conducting and insulating states. A total of 18 quantum chips are fabricated with 144 field effect hybrid Nb‐ Injats:sub0.75</jats:sub>Gajats:sub0.25</jats:sub>As 2DEG‐Nb quantum wires and the electrical response, switching voltage (on/off) statistics, quantum yield, and reproducibility of several devices at cryogenic temperatures are investigated. The proposed integrated quantum device architecture allows control of individual junctions in a large array on a chip useful for emerging cryogenic quantum technologies.</jats:p>