Stem cells "aclymatise" to regenerate the blood system.
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Abstract
How blood stem cells balance fate decisions between quiescence maintenance and differentiation during recovery from cancer treatment remains poorly understood. A recent study by Umemoto et al (2022) uncovers an unexpected linkage between metabolic and epigenetic regulation of haematopoiesis, suggesting new targets in haematopoietic regeneration, with possible implications in leukaemogenesis and therapy resistance.
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EMBO J
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0261-4189
1460-2075
1460-2075
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Springer Nature
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Except where otherwised noted, this item's license is described as All rights reserved
Sponsorship
Medical Research Council (MC_PC_17230)
MRC (MR/V005421/1)
Cancer Research UK (26670)
MRC (MR/V005421/1)
Cancer Research UK (26670)