Mg2+-driven selection of natural phosphatidic acids in primitive membranes

Biological membranes are composed exclusively of phospholipids comprising glycerol-1-phosphate or glycerol-3-phosphate. By contrast, primitive membranes would likely have been composed of heterogeneous mixtures of phospholipids, including non-natural analogues comprising glycerol-2-phosphate,...

Description

Acknowledgements: The project was funded by the Foundation Jean-Marie Lehn, the University of Strasbourg Institute for Advanced Study (USIAS) and the Agence Nationale de la Recherche (ITI SysChem within the Investissement d’Avenir program ANR-10-IDEX-0002, and AAP IdEx 2022 Attractivité to C. B.), and the CSC Graduate School, funded by the Agence Nationale de la Recherche (CSC-IGS ANR-17-EURE-0016 to K. T. M. and V. J. B. T.). The authors gratefully acknowledge support from Foundation Jean-Marie Lehn, the University of Strasbourg Institute for Advanced Study and the Agence Nationale de la Recherche. The authors thank colleagues at ISIS and lab members for stimulating discussions.

Keywords

3405 Organic Chemistry, 34 Chemical Sciences

Journal Title

Chemical Science

Journal ISSN

2041-6520
2041-6539

Publisher

Royal Society of Chemistry (RSC)

Publisher DOI

https://doi.org/10.1039/d4sc05362a

Rights and licensing

Except where otherwised noted, this item's license is described as https://creativecommons.org/licenses/by-nc/3.0/

Sponsorship

Agence Nationale de la Recherche (ANR-10-IDEX-0002, CSC-IGS ANR-17-EURE-0016, AAP IdEx 2022)
Université de Strasbourg (Unassigned)

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